FAQ
February 03, 2026
FAQ: How Do You Use the Dexamethasone Suppression Test?
In this FAQ video, David Doriguzzi, PA-C, breaks down how to screen for hypercortisolism using the 1 mg dexamethasone suppression test (DST). He explains the physiology behind cortisol suppression, how to correctly interpret post-dexamethasone cortisol levels, and why results that appear “low” on lab reports may actually be abnormal. The discussion also reviews the value of measuring dexamethasone levels, ACTH, and DHEAS to help differentiate adrenal versus pituitary causes of cortisol excess. Designed for APPs and clinicians managing patients with difficult-to-treat type 2 diabetes and suspected hypercortisolism.
Thank you to Corcept Therapeutics for sponsoring this FAQ Video Module.